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Literature summary extracted from

  • Basak, S.; Chretien, M.; Mbikay, M.; Basak, A.
    In vitro elucidation of substrate specificity and bioassay of proprotein convertase 4 using intramolecularly quenched fluorogenic peptides (2004), Biochem. J., 380, 505-514.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.21.B24 stable transfection of Hi5 cells with a rat PCAA vector, infection of BSC-40 cells with a recombinant vaccinia virus carrying the rat PC4A cDNA Rattus norvegicus

Protein Variants

EC Number Protein Variants Comment Organism
3.4.21.B24 additional information PC4-null mice Mus musculus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.21.B24 54000
-
 Western blot analysis, mature PCA Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.B24 Mus musculus
-
-
-
3.4.21.B24 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.B24 additional information sperm Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.B24 A-disintegrin and metalloproteinase-like-1 + H2O
-
 Mus musculus ?
-
 ?
3.4.21.B24 A-disintegrin and metalloproteinase-like-2 + H2O
-
 Mus musculus ?
-
 ?
3.4.21.B24 A-disintegrin and metalloproteinase-like-3 + H2O
-
 Mus musculus ?
-
 ?
3.4.21.B24 A-disintegrin and metalloproteinase-like-5 + H2O
-
 Mus musculus ?
-
 ?
3.4.21.B24 acetyl-KTKQLR-7-amido-4-methylcoumarin + H2O most efficiently and selectively cleaved Mus musculus acetyl-KTKQLR + 7-amino-4-methylcoumarin
-
 ?
3.4.21.B24 additional information digestion of intramolecularly quenched fluorogenic peptides by PC4 Mus musculus ?
-
 ?
3.4.21.B24 pERTKR-4-methyl coumaryl-7-amide + H2O exhibits a gradual increase in cleavage with the amount of PC4 used Mus musculus ?
-
 ?
3.4.21.B24 pro-insulin growth factor-I + H2O
-
 Mus musculus ?
-
 ?
3.4.21.B24 pro-insulin growth factor-II + H2O
-
 Mus musculus ?
-
 ?
3.4.21.B24 pro-pituitary adenylate cyclase-activating polypeptide + H2O
-
 Mus musculus ?
-
 ?
3.4.21.B24 t-butyloxycarbonyl-RVRR-4-methyl coumaryl-7-amide + H2O
-
 Mus musculus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.21.B24 PC4
-
 Mus musculus
3.4.21.B24 PC4
-
 Rattus norvegicus